Métodos de síntesis de chalconas

Autores/as

  • Gustavo Antonio Pasquale Centro de Investigación en Sanidad Vegetal (CISaV) / Curso de Química Orgánica. Facultad de Ciencias Agrarias y Forestales, UNLP
  • Diego Manuel Ruiz Centro de Investigación en Sanidad Vegetal (CISaV) / Curso de Química Orgánica. Facultad de Ciencias Agrarias y Forestales, UNLP

Palabras clave:

chalconas, flavanona, síntesis orgánica

Resumen

Este trabajo de recopilación trata de mostrar el estado del arte en relación a las diferentes formas que presenta la investigación en la síntesis de chalconas, las cuales representan una familia de compuestos que no solo son excelentes reactivos para la síntesis orgánica, sino que también poseen múltiples propiedades biológicas y medicinales.

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Citas

M.N. Gomes, E.N. Muratov, M. Pereira, J.C. Peixoto, L.P. Rosseto, P.V.L. Cravo, C.H. Andrade, B.J. Neves. “Chalcone Derivatives: Promising Starting Points for Drug Design”. Molecules, 22, 2017, 1210

P. Jaiswal, D.P. Pathak, H. Bansal, U. Agarwal. “Chalcone and their Heterocyclic Analogue: A Review Article”. J Chem. Pharm. Res., 10, 2018, 160-173.

D. Mulugeta, B. Abdica, A. Belay, M. Endale. “Synthesis of Chalcone and Flavanone Derivatives using ZnO Nanoparticle as Catalyst for Antibacterial Activity” Chem. Mater. Res. 10, 2018, 1-11.

D. Septianingtyas, N. Zafira, Zulhipri, F. Kurniadewi, H. Dianhar. “Green synthesis of chalcones derivatives” AIP Conference Proceedings 2331, 2021, 040020.

T. Narender, K. Papi Reddy. “A simple and highly efficient method for the synthesis of chalcones by using borontrifluoride-etherate”. Tetrahedron Lett., 48, 2007, 3177-3180.

B.M. Choudary, K.V.S. Ranganath, Jagajit Yadav, M. Lakshmi Kantam. “Synthesis of flavanones using nanocrystalline MgO”. Tetrahedron Lett., 46, 2005, 1369-1371.

J.B. Harborne. The Flavonoids. Advances in Research Science. Chapman and Hall, Londres, 1986.

Z. Arlindo Pascual, S. Carrera González. “Síntesis de Chalconas: Estructuras Privilegiadas en la Síntesis de Heterociclos con Actividad Biológica”. Psychologia Latina. 2018. Vol. Especial, 20-23.

P. Patil, P. Amjad Khan, S. Zangade. “Synthesis of 1, 3-diaryl-2-propene-1-one derivatives using Tripotassium phosphate as an alternative and efficient catalyst and study its cytotoxic and antimicrobial properties” Curr. Chem. Lett., 9, 2020, 183–198.

G. Thirunarayanan, K. Thirumurthy, G. Vanangamudi, M. Subramanian, R. Arulkumaran, D. Kamalakkannan, R. Sundararajan, S.P. Sakthinathan, S. Vijayakumar, K. Ranganathan, R. Suresh. “Fly-ash:water catalyzed greener synthesis and insect antifeedant activities of some chalcones”. Elixir Org. Chem. 45, 2012, 7898-7905.

S.W. Kahssay, G.S. Hailu, K.T. Desta. “Design, Synthesis, Characterization and in vivo Antidiabetic Activity Evaluation of Some Chalcone Derivative”. Drug Des. Devel. Ther., 15, 2021, 3119-3129.

Z. Nowakowska, Z. “A review of anti-infective and anti-inflammatory chalcones”. Eur. J. Med. Chem. 42, 2007, 125-137.

G. Tyrunarayanan, S. Surya, S. Srinivasan, G. Vanangamudi, V. Sathiyendiran,V. “Synthesis and insect antifeedant activities of some substituted styryl 3,4-dichlorophenyl ketones”. Spectrochim. Acta A, 75, 2010, 152-156.

X. Tang, S. Su, M. Chen, J. He, R. Xia, T. Guo, Y. Chen, C. Zhang, J. Wang, W. Xue “Novel chalcone derivatives containing a 1,2,4-triazine moiety: design, synthesis, antibacterial and antiviral activities”. RSC Adv., 9, 2019, 6011-6020.

T. Guo, R. Xia, M. Chen, J. He, S. Su, L. Liu, X. Li, W. Xue. “Biological activity evaluation and action mechanism of chalcone derivatives containing thiophene sulfonate”. RSC Adv., 9, 2019, 24942-24950.

G. Thirunarayanan, G. Vanangamudi. “Insect antifeedant potent chalcones”. J. Indian Chem. Soc. 85, 2008, 447-451.

H. Jin, Y. Geng, Z. Yu, K. Tao, T. Hou. “Lead optimization and anti-plant pathogenic fungi activities of daphneolone analogues from Stellera chamaejasme L”. Pest Biochem. Physiol. 93, 2009, 133-137.

S-H. Lee, J.Y. Choi, B.R. Lee, Y. Fang, J.H. Kim, D.H. Park, M.G. Park, R.M. Woo, W.J. Kim, Y.H. Je. “Insect growth regulatory and larvicidal activity of chalcones

against Aedes albopictus” Entomol. Res., 48, 2018, 55–59.

G. Pasquale, G. Romanelli, J. Autino, J. García, E. Ortiz, P. Duchowicz. “Quantitative structure–activity relationships of mosquito larvicidal chalcone derivatives” J. Agric.Food Chem. 60, 2012, 692-697.

S.R. Satyavani, S. Kanjilal, M.S. Rao, R.B.N. Prasad, U.S.N. Murthy. “Synthesis and mosquito larvicidal activity of furanochalcones and furanoflavonoids analogous to karanjin”. Med. Chem Res, 24, 2015, 842-850.

R. Sundararajan, R. Arulkumaran, S. Vijayakumar, D. Kamalakkannan, R. Suresh, S. John Joseph, K. Ranganathan, S. P. Sakthinathan, G. Vanangamudi, G. Thirunarayanan. “Assessment of Substituent Effects and Antimicrobial Activities of some 2ʹ,5ʹ-Dimethyl Phenyl Chalcones”. Int. Lett. Chem. Phys. Astron., 1, 2014. 67-73.

M.J. Climent, A. Corma, S. Iborra, J. Primo, J. “Base Catalysis for Fine Chemicals Production: Claisen-Schmidt Condensation on Zeolites and Hydrotalcites for the Production of Chalcones and Flavanones of Pharmaceutical Interest” J. Catal., 151, 1995, 60-66.

M. Ritter, R.M. Martins, S.A. Rosa, J.L. Malavolta, R.G. Lund, A.F.C. Flores, C.M.P. Pereira. “Green Synthesis of Chalcones and Microbiological Evaluation”. J. Braz. Chem. Soc., 26, 2015, 1201-1210.

G.D. Carlo, N. Mascolo, A.A. Izzo, F. Capasso. “Flavonoids: old and new aspects of a class of natural therapeutic drugs”. Life Sci. 65, 1999, 337-353.

H. Yin, X. Shi, H. Wang, G. Liu, L. Ma. “VB1 Promoted Green Synthesis of Chalcones and Its Neuroprotection Potency Evaluation”. Processes, 7, 2019, 236

D. Mulugeta. “Synthesis of Chalcone and Flavanone Derivatives using ZnO Nanoparticle as Catalyst for Antibacterial Activity”. Chem. Mater. Res. 10, 2018, 1-11.

M.J. Climent, A. Corma, S. Iborra, A. Velty. “Activated hydrotalcites as catalysts for the synthesis of chalcones of pharmaceutical interest”. J. Catal., 221, 2004, 474-482.

P. Patil, P.A. Khan, S. Zangade”. Synthesis of 1, 3-diaryl-2-propene-1-one derivatives using Tripotassium phosphate as an alternative and efficient catalyst and study its cytotoxic and antimicrobial properties”. Curr. Chem. Lett., 9, 2020, 183–198.

A.H. Shntaif. “Green Synthesis of Chalcones under microwave Irradiation”. ChemTech., 9, 2016, 36-39.

P. Kulkarni. “Calcium Oxide Catalyzed Synthesis of Chalcone Under Microwave Condition”. Curr. Microwave Chem., 2, 2015, 144-149

A. Patel, I. Panchal, I. Parmar, B. Mishtry. “Synthesis of New Flavanoid and Chalcone derivatives as antimicrobial agent by Green Chemistry Approach”. Int. J. Pharm. Sci. Res., 8, 2017, 2725-2730.

G. Ibieta Jiménez, J.A. Bravo, J.L. Vila. “Synthesis of Benzylideneacetophenone under Microwave Irradiation” Rev. Bol. Quim., 33, 2016, 179-182.

L.C.C. Vieira, M. Weber Paixão, A.G. Corrêa. “Green synthesis of novel chalcone and coumarin derivatives via Suzuki coupling reaction”. Tetrahedron Lett., 53, 2012, 2715–2718.

J-T. Li, S-X. Wang, G-F. Chen, T-S. Li. “Some Applications of Ultrasound Irradiation in Organic Synthesis”. Curr. Org. Synth., 2, 2005, 415-436.

J-T. Li, W-Z. Yang, S-X. Wang, S-H. Li, T-S. Li. “Improved synthesis of chalcones under ultrasound irradiation”. Ultrason. Sonochem., 9, 2002, 237–239.

V. Calvino, M. Picallo, A.J. Lopez-Peinado, R.M. Martin-Aranda, C.J. Duran-Valle. “Ultrasound accelerated Claisen–Schmidt condensation: A green route to chalcones”. Appl. Surf. Sci.,252, 2006, 6071-6074.

N. Cancio, A.R. Costantino, G.F. Silbestri, M.T. Pereyra. “Ultrasound-Assisted Syntheses of Chalcones: Experimental Design and Optimization”. Proceedings. 41, 2019, 13.

G. Rothenberg, A.P. Dowine, C.L. Raston, J.L. Scott. “Understanding Solid/Solid Organic Reactions” J. Am. Chem. Soc., 123, 2001, 8701-8708.

S. Zangade, S. Mokle, A. Vibhute, Y. Vibhute. “An Efficient and Operationally Simple Synthesis of Some New Chalcones by Using Grinding Technique”. Chem. Sci. J. 2011, 2011-CSJ-13.

G. Senthilkumar, K. Neelakandan, H. Manikandan. “A convenient, green, solvent free synthesis and characterization of novel fluoro chalcones under grind-stone chemistry”. Der Chemica Sinica, 5, 2014, 106-113.

D.R. Palleros. “Solvent-Free Synthesis of Chalcones”. J. Chem. Educ., 81, 2004 1345–1347

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Publicado

2022-07-25

Cómo citar

Pasquale, G. A., & Ruiz, D. M. (2022). Métodos de síntesis de chalconas. Investigación Joven, 9(1), 13–17. Recuperado a partir de https://revistas.unlp.edu.ar/InvJov/article/view/14090

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