Métodos sostenibles para la síntesis de cromenos: avances recientes

María Emilia Pérez; Eliana Rocío Nope Vargas

doi:10.24215/23143991e006

Autores/as

María Emilia Pérez Universidad Nacional de La Plata, Argentina https://orcid.org/0009-0009-8416-7839
Eliana Rocío Nope Vargas Universidad Nacional de La Plata, Argentina https://orcid.org/0000-0002-9653-3527

DOI:

https://doi.org/10.24215/23143991e006

Palabras clave:

síntesis, cromenos, heterociclo, reacción multicomponente, catalizador heterogéneo

Resumen

La búsqueda de procesos químicos ambientalmente amigables y alineados con los principios de la Química Verde ha cobrado un interés creciente en los últimos años. En este contexto, la síntesis multicomponente ha emergido como una estrategia clave en Química Orgánica, permitiendo la obtención de heterociclos con potencial actividad biológica, como los cromenos. Estos compuestos poseen un alto valor en la industria farmacéutica y exhiben un amplio espectro de bioactividades. En consecuencia, se han desarrollado diversas metodologías para su síntesis, junto con una amplia gama de materiales catalíticos. Entre los enfoques más estudiados destacan la irradiación por microondas y ultrasonido, debido a su eficiencia y sostenibilidad. En esta revisión, se presentan y analizan los métodos de síntesis que cumplen con los principios de la Química Verde, promoviendo procesos altamente sostenibles y de menor impacto ambiental.

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