Vía intranasal: una alternativa para la administración de fármacos de acción central en equinos

Administración intranasal de fármacos

  • María Inés Velloso Facultad de Ciencias Veterinarias. Universidad Nacional de La Plata.
  • Violeta Ferreira Facultad de Ciencias Veterinarias. Universidad Nacional de La Plata.
  • Mariangeles Vita Facultad de Ciencias Veterinarias. Universidad Nacional de La Plata.
  • María Fabiana Landoni Facultad de Ciencias Veterinarias. Universidad Nacional de La Plata.
Palabras clave: Via Intranasal, fármacos de acción central, pasaje nariz-cerebro, equinos

Resumen

La vía intranasal es reconocida en medicina humana como una vía muy promisoria para la administración sistémica y cerebral de fármacos. Es una vía de administración indolora, incruenta, económica y práctica. Por sus características, es muy útil para la aplicación de fármacos en pacientes con alteraciones orales, con diarrea o que no cooperen. Además, es una potencial vía directa al sistema nervioso central (SNC). Su uso en medicina veterinaria es muy raro, salvo para la administración de tratamientos locales. En la especie equina, aun cuando no hay estudios completos y profundos sobre las características anatomofisiológicas de la cavidad nasal, su gran superficie e irrigación (área potencial de absorción) permiten inferir su viabilidad para la administración sistémica de fármacos. En el presente artículo se discuten las características de la cavidad nasal de los equinos en relación a las diversas vías de absorción sistémica y del transporte nariz-cerebro
de fármacos, así como las potenciales aplicaciones de esta vía de administración.

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Publicado
2019-06-19
Cómo citar
Velloso, M. I., Ferreira, V., Vita, M., & Landoni, M. F. (2019). Vía intranasal: una alternativa para la administración de fármacos de acción central en equinos. Analecta Veterinaria, 39(1), 033. https://doi.org/10.24215/15142590e033
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