Modificación de memorias maladaptativas durante el sueño y la vigilia: una visión interidisciplinaria

Matías Bonilla; Camila Isabel Jorge; Malen Daiana Moyano; Cecilia Forcato

doi:10.24215/2422572Xe073

Autores/as

Matías Bonilla Instituto Tecnológico de Buenos Aires (ITBA) (Argentina)
Camila Isabel Jorge Instituto Tecnológico de Buenos Aires (ITBA) (Argentina)
Malen Daiana Moyano Instituto Tecnológico de Buenos Aires (ITBA) (Argentina)
Cecilia Forcato Instituto Tecnológico de Buenos Aires (ITBA) (Argentina)

DOI:

https://doi.org/10.24215/2422572Xe073

Palabras clave:

reactivación, memoria emotiva, sueño, trastornos de ansiedad

Resumen

Las memorias consolidadas pueden atravesar por un período de labilidad frente a la presentación de recordatorios (claves ligadas al aprendizaje inicial), seguido de un proceso de re-estabilización conocido como reconsolidación. Por otro lado, el sueño tiene un rol activo en la formación y modificación de memorias, así como en la reducción del tono emocional de las experiencias. Durante el mismo, las nuevas memorias se reactivan, refuerzan e integran a las redes mnésicas preexistentes. Dentro del contexto terapéutico, se pueden evocar memorias antiguas según la necesidad del sujeto, lo que podría estar desencadenando constantes labilizaciones/reestabilizaciones, quizás sin ser conscientes de ello. En la presente revisión bibliográfica discutimos los avances neurocientíficos relacionados a la reactivación y modificación de memorias durante la vigilia y el sueño, así como los últimos desarrollos en terapias psicoterapéuticas para trastornos de ansiedad, con el objetivo de pensar una práctica más interdisciplinaria.

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Biografía del autor/a

Matías Bonilla, Instituto Tecnológico de Buenos Aires (ITBA) (Argentina)

Estudiante avanzado de psicología (100% de las materias aprobadas, en la espera de defensa de tesis a causa de COVID-19). Estudiante doctoral, integrante del Laboratorio de Sueño y Memoria, departamento de Bioingeniería, ITBA. Actualmente me encuentro estudiando la formación de falsas memorias en diferentes rangos etarios.

Camila Isabel Jorge, Instituto Tecnológico de Buenos Aires (ITBA) (Argentina)

Estudiante de Psicología (UBA).

Malen Daiana Moyano, Instituto Tecnológico de Buenos Aires (ITBA) (Argentina)

Lic. en Biotecnología (UNQ). Actualmente becaria Doctoral CONICET en el Lab de Sueño y Memoria, Depto de Bioingeniería, ITBA. Estudio los mecanismos vinculados a la formación y modificación de memorias declarativas en humanos.

Cecilia Forcato, Instituto Tecnológico de Buenos Aires (ITBA) (Argentina)

Soy Lic. en Ciencias Biológicas de la Universidad de Buenos Aires, Doctora en el área de Ciencias Biológicas (UBA), Investigadora Adjunta CONICET, Profesora Asociada del Insituto Tecnológico de Buenos Aires y Docente de la Maestría en Neurociencias UNAJ. Soy Directora del Laboratorio de Sueño y Memoria, Depto de Bioingeniería, ITBA. Mis líneas de investigación se centran en el estudio de la modificación e integración de memorias durante el sueño y la vigilia, reforzamiento de memorias declarativas en adultos jóvenes, mayores y con deterioro cognitivo leve. Formación de falsas memorias en hechos delictivos. Sueño lúcido y experiencias fuera del cuerpo iniciadas desde la parálisis del sueño.

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