<i>Escherichia coli</i> con resistencia a múltiples antimicrobianos en granjas de producción porcina de la República Argentina

Abstract

The objectives of this study were: i) to control the resistance of E. coli against various commonly used antimicrobials for therapeutic and prophylactic in pig farms ii) to isolate and characterize phenotypic and genotypic E. coli toxigenic diarrhea from pigs pre and post weaning, iii) to determinate the presence of class 1 and 2 integrons as possible resistance mechanism of spread of E. coli from porcine. Rectal swabs were processed from 216 clinically healthy and diarrheic pigs, from 15 pig farms. 46.6% of the isolates were resistant to multiple antimicrobials, 93% were resistant to tetracycline, 59% to ciprofloxacin, 52% to florfenicol, 8% to amoxicillin/clavulanic acid and 0.6% to gentamicin. No resistance to colistina was observed. Out of 56 E. coli, 34 carried at least one gene int2 or int1. Toxigenic E. coli was isolated from 53% of pigs with diarrhea. The inappropriate use of antimicrobial to prophylactic or therapeutic purposes in veterinary medicine, involves a risk to public health.