Rutas de síntesis enmarcadas dentro de los parámetros de la química verde para la producción de 1,4-Dihidropiridinas

  • Luisa Fernanda Gutiérrez Universidad Pedagógica y Tecnológica de Colombia. Av. Central del Norte 39-115. Tunja, Boyacá, Colombia
  • Gloria Astrid Prieto Suarez Universidad Pedagógica y Tecnológica de Colombia. Av. Central del Norte 39-115. Tunja, Boyacá, Colombia
Palabras clave: Química verde, 1, 4-Dihidropiridinas, Síntesis, Catalizador

Resumen

Las 1,4-dihidropiridinas (1,4-DHPs) son compuestos heterocíclicos de gran importantes en la industria farmacológica,  por lo tanto es uno de los objetivos sintéticos más atractivos de la química orgánica. Su síntesis clásica se lleva a cabo mediante la reacción de  Hantzsch, sin embargo, nuevas estrategias han surgido alrededor de la modificación de esta, con el fin de mejorar su eficiencia y minimizar su impacto ambiental. Los avances en la implementación de nuevas alternativas para la síntesis de 1,4-dihidropiridinas, que se enmarquen dentro de los parámetros de la química verde se enuncian en la presente revisión.

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Citas

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Publicado
2016-09-07
Cómo citar
Gutiérrez, L. F., & Prieto Suarez, G. A. (2016). Rutas de síntesis enmarcadas dentro de los parámetros de la química verde para la producción de 1,4-Dihidropiridinas. Investigación Joven, 3(1). Recuperado a partir de https://revistas.unlp.edu.ar/InvJov/article/view/2764
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